26 Sep 1798 - Birth of his biological father Isaac Otis at Saratoga Springs, Saratoga County, New York, USA 

20 Aug 1802 - Birth of his biological mother Caroline Curtiss at Michigan, USA 

25 Jan 1827 - Marriage of parents at Homer, Cortland County, New York, USA 

13 Dec 1827 - Birth at Cortland, Cortland County, New York, USA 

Feb 1837 - (9 years) Birth of his wife Amelia Harres at Philadelphia, Philadelphia County, Pennsylvania, USA 

12 Mar 1858 - (30 years) Death of his biological father Isaac Otis at Prairieville Township, Barry County, Michigan, USA 

Mar 1858 - (30 years) Burial of his biological father Isaac Otis at Prairie Home Cemetery, Richland, Kalamazoo County, Michigan, USA 

22 Apr 1862 - (34 years) Marriage with Amelia Harres at Philadelphia, Philadelphia County, Pennsylvania, USA 

28 Feb 1869 - (41 years) Birth of his daughter Amelia Otis at Atchison, Atchison County, Kansas, USA 

12 Mar 1883 - (55 years) Death of his biological mother Caroline Curtiss at Kalamazoo, Kalamazoo County, Michigan, USA 

Mar 1883 - (55 years) Burial of his biological mother Caroline Curtiss at Prairie Home Cemetery, Richland, Kalamazoo County, Michigan, USA 

12 Feb 1912 - (84 years) Death of his wife Amelia Harres at Atchison, Atchison County, Kansas, USA 

Feb 1912 - (84 years) Burial of his wife Amelia Harres at Mount Vernon Cemetery, Atchison, Atchison County, Kansas, USA 

9 May 1912 - (84 years) Death at Atchison, Atchison County, Kansas, USA 

May 1912 - (84 years) Burial at Mount Vernon Cemetery, Atchison, Atchison County, Kansas, USA 

29 Oct 1962 - Death of his daughter Amelia Otis at Medford, Middlesex County, Massachusetts, USA 

1962 - Burial of his daughter Amelia Otis at Donated to Medical Science. Specifically: Donated to Harvard Medical School